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                               April 19, 2022

       Mostafa Ronaghi, Ph.D.
       Chief Executive Officer
       Dynamics Special Purpose Corp.
       2875 El Camino Real
       Redwood City, CA, 94061

                                                        Re: Dynamics Special
Purpose Corp.
                                                            Amendment No. 1 to
Registration Statement on Form S-4
                                                            Filed April 1, 2022
                                                            File No. 333-262707

       Dear Dr. Ronaghi:

             We have reviewed your amended registration statement and have the
       comments. In some of our comments, we may ask you to provide us with
information so we
       may better understand your disclosure.

              Please respond to this letter by amending your registration
statement and providing the
       requested information. If you do not believe our comments apply to your
facts and
       circumstances or do not believe an amendment is appropriate, please tell
us why in your

              After reviewing any amendment to your registration statement and
the information you
       provide in response to these comments, we may have additional comments.
Unless we note
       otherwise, our references to prior comments are to comments in our March
13, 2022 letter.

       Amendment No. 1 to Registration Statement on Form S-4 filed April 1,

       Market and Industry Data, page ii

   1.                                                   We note your response
to prior comment 3 and reissue the comment. Please
                                                        revise to clarify that
you are responsible for all disclosure in the prospectus.
       Background of the Business Combination, page 112

   2.                                                   We note your response
to prior comment 9 and reissue the comment. Please provide the
                                                        exact number of shares
that will have registration rights after the consummation of the
                                                        business combination.
 Mostafa Ronaghi, Ph.D.
Dynamics Special Purpose Corp.
April 19, 2022
Page 2
3.    We note your response to prior comment 21 and reissue the comment in
part. Please
      clarify whether the $240,000,000 equity valuation of Senti was subject to
any negotiation
      between the parties.
4.    We note within your disclosure on page 115 you reference financial
projections provided
      by Senti Biosciences, Inc. to DYNS. Please disclose these projections and
discuss in
      detail how the projections were considered and used by management and the
board in
      evaluating the transaction.
The Board's Reasons for Approval of the Business Combination, page 127

5.    We note your response to prior comment 25 and your revised disclosure on
page 127.
      Please expand your discussion of the Comparable Company Analysis to
identify the
      specific financial information used in the analyses and provide an
illustrated table to
      show the multiples used in comparison to Senti Biosciences, Inc.
Unaudited Pro Forma Condensed Financial Information, page 159

6.    We note your response to prior comment 33. Please further expand your
disclosures to
      disclose the actual calculation of the 0.1953 assumed exchange ratio
rather than merely
      referring to certain terms in the Business Combination Agreement. In that
regard, your
      disclosures should clearly outline how the exchange ratio was calculated
      disclosing the amounts related to terms such as the Fully Diluted Company
      (as defined in the Business Combination Agreement).
       You may contact Ameen Hamady at 202-551-3891 or Wilson Lee at
202-551-3468 if you
have questions regarding comments on the financial statements and related
matters. Please
contact Isabel Rivera at 202-551-3518 or Jeffrey Gabor at 202-551-2544 with any

FirstName LastNameMostafa Ronaghi, Ph.D.
                                                            Division of
Corporation Finance
Comapany NameDynamics Special Purpose Corp.
                                                            Office of Real
Estate & Construction
April 19, 2022 Page 2
cc:       Alan Denenberg
FirstName LastName